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steroid Patients were also required to have at least one year of continuous enrollment before the study period (1 January 2011 to 31 December 2011) to capture past use of corticosteroids and baseline comorbid conditions. To focus on new users, we excluded those who received any oral corticosteroids during 2011 (n=293456). In addition, we excluded from the study cohort enrollees exclusively receiving non oral forms of corticosteroids (eg steroids drugs, inhaler steroids drugs, intravenous route, or intra articular injections only) or prescriptions for oral budesonide (n=102243) steroids drugs, and those with solid organ or bone marrow transplants steroids drugs, or malignancy (n=224658) (see web appendix table 1). steroid

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